Read our privacy policy. Other side effects not listed above may also occur in some people. This can cause serious side effects that affect your liver. You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines. How do COVID-19 antibody tests differ from diagnostic tests? Do not give Alprim to anyone else, even if they have the same condition as you. do not look quite right. The more medicines you take, the more difficult it can be to remember important information about them. Take Alprim on an empty stomach, 1 hour before or 2 hours after meals. any type of skin rash which includes itching and redness, tiredness which may occur together with headaches, sore mouth or tongue, weight loss or yellowing of the eyes or skin. Heat and dampness can destroy some medicines. If you become pregnant while taking ALPRIM, tell your doctor immediately. ALPRIM tablets are best taken before bedtime. Do not take Alprim after the expiry date (EXP) printed on the pack. Do not take any other medicines while you are taking ALPRIM without first telling your doctor. Fever in infants and children: Pathophysiology and management. They may differ from the information contained in this leaflet. There are 129 drugs known to interact with trimethoprim, along with 3 disease interactions. This medication also contains an ingredient that helps to make the urine acidic. Accessed March 25, 2020. ACE inhibitors, medicines used to treat high blood pressure and some heart conditions. Do not leave ALPRIM in the car or on window sills. Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from a pharmacy, supermarket or health food shop. There is no information concerning the right dose for children under the age of 6 Taking ALPRIM with food will help reduce the chance of a stomach upset. Tell your doctor if you have, or have had, any medical conditions, especially the following: Your doctor may want to take special care if you have any of these conditions. Other side effects not listed above may also occur in some people. Do not take a double dose to make up for the dose you missed. If it is near the time of the next dose, skip the missed dose. There is no information concerning the right dose for children under the age of 6 years. If you have not told your doctor about any of the above, tell him/her before you start taking ALPRIM. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Tell your doctor if you notice anything that is making you feel unwell. ALPRIM tablets are best taken before bedtime. There is the possibility of megaloblastic anaemia developing in patients prescribed trimethoprim whilst taking pyrimethamine for malarial prophylaxis. Do not take Alprim if the packaging is torn or shows signs of tampering or the tablets do not look quite right. Thyroid disease: challenges in primary care, pyrimethamine, a medicine used to prevent malaria, warfarin, a medicine used to prevent blood clots, methotrexate, a medicine used to treat arthritis and some types of cancer, phenytoin, a medicine used to control epilepsy (fits or seizures), digoxin, a medicine used to treat heart failure or to control a fast irregular heart beat, procainamide, a medicine used to correct an irregular heart beat or to slow an over active heart, zidovudine, zalcitabine or lamivudine; medicines used for certain viral infections, dapsone, a medicine used for leprosy or dermatitis herpetiformis, ciclosporin, a medicine used to help prevent organ transplant rejection or to treat certain problems with the immune system, diuretics, also known as fluid or water tablets. Do not store ALPRIM or any other medicine in the bathroom or near a sink. You may need to read it again. The expiry date can be found on the packaging. ALPRIM passes into breast milk and may affect your baby. Improving clinical practice and health outcomes for Australia. Multisystem inflammatory syndrome in children (MIS-C), Safe outdoor activities during the COVID-19 pandemic, Safety tips for attending school during COVID-19, Fever treatment Quick guide to treating a fever. Alprim will not work against infections caused by viruses, such as colds or flu. In fact, fevers seem to play a key role in fighting infections. Sometimes they are serious, most of the time Swallow the tablets whole with a glass of water. Do not leave Alprim in the car or on window sills. For most infections, ALPRIM is usually taken for 7 days. But in . For years, products containing acetaminophen, such as the pain reliever Tylenol, were largely viewed as safe to take during pregnancy. Alprim is available only with a doctors prescription. other information we have about you. You may need to have regular blood tests. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. These people may include the elderly, people with folate deficiency and people taking certain medicines. Because trimethoprim may interfere with folic acid metabolism, caution should be exercised when trimethoprim is administered to a nursing woman. May employ gastric lavage and forced diuresis. Fever. Call the doctor if the fever doesn't respond to the medication or lasts longer than three days. Click here for an email preview. Tell your doctor if you are pregnant or plan to become pregnant. This website uses cookies. Talk to your doctor about the need for additional contraception while taking ALPRIM. Tell your doctor if you have, or have had, any medical conditions, especially the following: Your doctor may want to take special care if you have any of these conditions. If we combine this information with your protected Alphapharm Pty Ltd trading as Viatris Level 1, 30 The Bond30-34 Hickson RoadMillers Point NSW 2000www.viatris.com.auPhone: 1800 274 276. Other reported clinical experience has not identified differences in response between the elderly and younger patients. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking ALPRIM. Alprim is associated with a greater risk of acute kidney injury and hyperkalaemia compared with other antibiotics used to treat UTIs, but not a greater risk of death. If you are taking Alprim for a long time, visit your doctor regularly so that they can check on your progress. Ask your doctor or pharmacist to answer any questions you may have. By Kelly Bilodeau, Former Executive Editor, Harvard Women's Health Watch. from light. Use of blood thinners requires caution with other drugs, especially painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs). Medication isn't needed. NPS MedicineWise disclaims all liability (including for negligence) for any loss, damage or injury resulting from reliance on or use of this information. hepatic dysfunction. or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing Do not take ALPRIM if the packaging is torn or shows signs of tampering or the tablets do not look quite right. Cephalexin and Ibuprofen There also have been no reported interactions between cephalexin and ibuprofen (Advil, Motrin IB, NeoProfen). This information is not intended as a substitute for medical advice and should not be exclusively relied on to manage or diagnose a medical condition. Read the label carefully for proper dosage, and be careful not to give your child more than one medication containing acetaminophen, such as some cough and cold medicines. ALPRIM is a 9.5 mm white normal convex tablet marked "TM/300" on one side, "G" on the other. Enter other medications to view a detailed report. Alprim is used to treat infections of the urinary tract caused by bacteria. Each ALPRIM tablet contains 300 mg of trimethoprim. Merck Manual Professional Version. Practical information, tools and resources for health professionals and staff to help improve the quality of health care and safety for patients. ACE inhibitors, medicines used to treat high blood pressure and some heart conditions. Always discuss with your doctor any problems or difficulties during or after taking ALPRIM. These thermometers provide the most accurate measurement of core body temperature. Ask your doctor if you have any questions about why Alprim has been prescribed for you. proarrhythmic effects. For children 6 to 12 years, the usual dose is half a tablet daily. Adults and teenagers at least 12 years old: Do not take more than 1000 milligrams (mg) at one time or more than 4000 mg in 24 hours. Your doctor can tell you what to do if you are taking any of these medicines. Each ALPRIM tablet contains 300 mg of trimethoprim. These include: pyrimethamine, a medicine used to prevent malaria, warfarin, a medicine used to prevent blood clots, methotrexate, a medicine used to treat arthritis and some types of cancer, phenytoin, a medicine used to control epilepsy (fits or seizures), digoxin, a medicine used to treat heart failure or to control a fast irregular heart Check with your doctor as soon as possible if you have any problems while taking ALPRIM For adults and children over 12 years, the usual dose is one tablet daily. By clicking "Allow All" you agree to the storing of cookies on your device to enhance site navigation, Do not take ALPRIM if you are allergic to any other medicines containing trimethoprim or any of the ingredients listed at the end of this leaflet. Keep this leaflet with your medicine. Immediately telephone your doctor, or the Poisons Information Centre (telephone 13 11 26), or go to Accident and Emergency at the nearest hospital, if you think you or anyone else may have taken too much ALPRIM. ALPRIM is not recommended for use in children under 6 years of age, as the safety Encourage your child to rest and drink plenty of fluids. Do not take ALPRIM if you are allergic to any other medicines containing trimethoprim or any of the ingredients listed at the end of this leaflet. Ask your doctor if you have any questions about why ALPRIM has been prescribed for you. Keep track of medicines and access important health info any time and anywhere, especially in emergencies. It's usually not necessary to lower a fever - an elevated temperature is meant to help your body fight off the virus. If you become pregnant while taking ALPRIM, tell your doctor immediately. A locked cupboard at least one-and-a-half metres above the ground is a good place https://www.uptodate.com/contents/search. Panadol Osteo (acetaminophen), along with Generic Name: trimethoprim Product Name: Alprim. Making safe and wise decisions for biological disease-modifying antirheumatic drugs (bDMARDs) and other specialised medicines. Elsevier; 2020. https://www.clinicalkey.com. Keep taking Alprim until you finish the pack, or for as long as your doctor recommends. electrolyte imbalance. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. The active ingredient in ALPRIM is trimethoprim. These people may include the elderly, people with folate deficiency and people taking certain medicines. Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking Alprim. Use ALPRIM only as directed and consult a health care professional if pain or symptoms persist. Ask your doctor before using acetaminophen together with ethanol. Do not drive or operate machinery until you know how ALPRIM affects you. The side effects listed above are rare but serious and require urgent medical attention expiry date, ask your pharmacist what to do with any that are left over. For adults and children over 12 years, the usual dose is one tablet daily. Do not be alarmed by this list of possible side effects. Use Alprim only as directed and consult a healthcare professional if pain or symptoms persist. If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. If symptoms persist see your healthcare professional. Pyrimethamine, a medicine used to prevent malaria; Warfarin, a medicine used to prevent blood clots; Methotrexate, a medicine used to treat arthritis and some types of cancer; Phenytoin, a medicine used to control epilepsy (fits or seizures); Digoxin, a medicine used to treat heart failure or to control a fast irregular heartbeat; Procainamide, a medicine used to correct an irregular heartbeat or to slow an overactive heart; Zidovudine, zalcitabine or lamivudine; medicines used for certain viral infections; Dapsone, a medicine used for leprosy or dermatitis herpetiformis; Cyclosporin, a medicine used to help prevent organ transplant rejection or to treat certain problems with the immune system; Diuretics, also known as fluid or water tablets; ACE inhibitors, medicines used to treat high blood pressure and some heart conditions. Pathophysiology and treatment of fever in adults. Swallow the tablets whole with a glass of water. Parenting information is available at Parenthub.com.au, The Medical System Bulk Billing & Medicare, 10 tips for encouraging sharing (and discouraging self-interest) this Christmas. or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. If you are not sure whether you are taking any of these medicines, check with your doctor or pharmacist. If you take this medicine after the expiry date, it may not work as well. information and will only use or disclose that information as set forth in our notice of 20 years of helping Australians make better decisions about medicines, medical tests and other health technologies. Take Alprim by mouth with or without food as directed by your doctor, usually once or twice daily. These people ALPRIM helps most people with urinary tract infections, but it may have unwanted side effects in some people. For further information talk to your doctor. Following oral administration, 50% to 60% of trimethoprim is excreted in the urine within 24 hours, approximately 80% of which is unchanged parent drug. Nursing Mothers: Alprim is excreted in human milk. Encourage your child to rest and drink plenty of fluids. ALPRIM passes into breast milk and may affect your baby. If you are not sure whether you should start taking this medicine, talk to your doctor. Provides health professionals with timely, independent and evidence-based information Opens a new window The study researchers say their findings are enough to state that ibuprofen treatment for UTI isn't a safe recommendation because of the risk of serious upper urinary tract infections and other. Tell your doctor if you are breastfeeding or wish to breastfeed. Yes, getting a Covid-19 vaccine these days can be a bit of a pain, in more ways than one. Other side effects not listed above may also occur in some people. Of the total drug interactions, American Academy of Pediatrics; 2018. Follow all directions given to you by your doctor and pharmacist carefully. Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. Management: Symptomatic and supportive treatment. Alphapharm Pty Ltd trading as Viatris Do not stop taking ALPRIM, even if you feel better after a few days, unless advised headaches, confusion or mental depression. This is not a complete list of all possible side effects. Some medicines may be affected by Alprim or may affect how well it works. If it is almost time for your next dose, skip the dose you missed and take your next Keep your tablets in a cool dry place where the temperature stays below 30C and protect from light. even if you do not think the problems are connected with the medicine or are not listed This content does not have an English version. No, you should not drink alcohol while taking Alprim else you may experience unpleasant side effects such as fast heartbeats, warmth or redness under your skin, tingly feeling, nausea, and vomiting. severe rash with skin peeling, fever, chills and aching muscles. Immediately stop taking Alprim if skin rash or any other allergic reaction occurs. It works by stopping the growth of the bacteria that is causing your infection. Your doctor will tell you if this is necessary. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Fight coronavirus (COVID-19) transmission at home. beat, procainamide, a medicine used to correct an irregular heart beat or to slow an over Talk to your doctor about the need for additional contraception while taking ALPRIM. Do this even if there are no signs of discomfort or poisoning. Mayo Clinic Minute: How dirty are common surfaces? ALPRIM is not recommended for use in children under 6 years of age, as the safety and effectiveness of ALPRIM in this age group has not been established. doctor. Tell your doctor if you are breastfeeding or wish to breastfeed. Your doctor will tell you if this is necessary. Alprim 300 mg tablets: 9.5 mm white, normal convex, tablet marked TM/300 on one side, G on reverse. megaloblastic anaemia). If you take too much ALPRIM, you may experience the following: nausea, vomiting, dizziness, Infant fever (age 90 days or younger). Tell your doctor if you notice anything that is making you feel unwell. Wipe from front to back after. taking ALPRIM. Keep this leaflet with your medicine. Your infection may not clear completely if you stop taking your medicine too soon. However, if you experience nausea, you may take Alprim with food. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. This is not a complete list of all possible side effects. Alprim isn't the safest antibiotic to take in pregnancy. Usually avoid combinations; use it only under special circumstances. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Call the doctor, even if your child doesn't have any other signs or symptoms. Do not take Alprim after the expiry date (EXP) printed on the pack. Mayo Clinic; 2019. If your child seems uncomfortable, give your child acetaminophen (Tylenol, others) or ibuprofen (Advil, Motrin, others). If you have any concerns about taking this medicine, talk to your doctor or pharmacist. Ask your doctor about the risks and benefits of taking ALPRIM during pregnancy. health information, we will treat all of that information as protected health Of the total drug interactions, 7 are major, 68 are moderate, and 35 are minor. to store medicines. News-Medical.Net provides this medical information service in accordance The active ingredient in ALPRIM is trimethoprim. Do not stop taking ALPRIM, even if you feel better after a few days, unless advised by your doctor. There are 110 drugs known to interact with This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Heat and dampness can destroy some medicines. The active ingredient in ALPRIM is trimethoprim. May administer Ca folinate (5-15 mg daily) if bone marrow depression occurs. analyse site usage and support us in providing free open access scientific content. Other types of thermometers, such as ear (tympanic membrane) or forehead (temporal artery) thermometers, although convenient, provide less accurate temperature measurements. Level 1, 30 The Bond More info. ALPRIM is available only with a doctor's prescription. signs of frequent infections such as fever, chills, sore throat or mouth ulcers. of breath, pink or red itchy spots on the skin which may blister and progress to form raised, It does not contain all the available information. signs of frequent infections such as fever, chills, sore throat or mouth ulcers. Accessed March 25, 2020. Tell your doctor or pharmacist that you are taking ALPRIM before you start taking You may need to have regular blood tests. Data sources include IBM Watson Micromedex (updated 1 May 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Call the doctor if the fever doesn't respond to the medication or lasts longer than one day. Your doctor may have prescribed ALPRIM for another reason. Talk to your doctor about the need for additional contraception while taking Alprim. Certain psychiatric and weight loss medicationscan cause potentially harmful interactions with anesthetic medications. If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Each Alprim tablet contains 300 mg of trimethoprim. They may differ from the information contained in this leaflet. Ask your doctor about the risks and benefits of taking Alprim during pregnancy. Dinarello CA, et al. The most important warning sign that Alprim is causing a serious side effect is usually a change in skin color. It does not contain all the available information. ALPRIM is rated in Australia as a Category B3 drug for use in pregnancy. AHA ranks popular US diets for cardiovascular fitness. The elderly and people with kidney problems may need smaller doses. Some mixtures of medications can lead to serious and even fatal consequences. Tell your doctor if you are taking any other medicines, including any that you buy If you are not sure whether you should start taking this medicine, talk to your doctor. It is used for the temporary relief of pain from conditions such as muscle aches, toothaches, menstrual cramps, or headaches (including migraine). ALPRIM is used to treat infections of the urinary tract caused by bacteria. You may need to read it again. Ask your doctor about the risks and benefits of taking ALPRIM during pregnancy. ALPRIM passes into breast milk and may affect your baby. Up to 102 F (38.9 C) taken rectally for children ages 2-3, or taken orally for children older than 3. This leaflet answers some common questions about ALPRIM. Some of the symptoms of an allergic reaction may include red, itchy skin rashes, itching or hives; swelling of the face, lips or tongue which may cause difficulty in swallowing or breathing; wheezing or shortness of breath. Tell your doctor or pharmacist that you are taking Alprim before you start taking any other medicine. Check with your doctor as soon as possible if you have any problems while taking ALPRIM even if you do not think the problems are connected with the medicine or are not listed in this leaflet. Relevant, timely and evidence-based information for Australian health professionals and consumers. Download Bissoy App to talk Doctor online, Trimethoprim, Trimthoprime, Trimethoprimum, Trimetoprima, amoxicillin, doxycycline, ciprofloxacin, cephalexin, azithromycin, clindamycin, ceftriaxone, levofloxacin, Augmentin, amoxicillin / clavulanate. Taking blood thinners and NSAIDs together can raise the risk of bleeding. Do not take ALPRIM if you have: a severe blood disorder or anaemia severe kidney problems. Always discuss with your doctor any problems or difficulties during or after taking Tell all the doctors, dentists and pharmacists who are treating you that you are taking ALPRIM. Your infection may not clear completely if you stop taking your medicine too soon. Tell your doctor if you are allergic to any other medicines, foods, dyes or preservatives. You may need medical treatment if you get some of the side effects. Is there an association between the consumption of ultra-processed food and adverse microbiota-gut-brain axis implications? or anyone else may have taken too much ALPRIM. Give your child acetaminophen (Tylenol, others). Check with your doctor as soon as possible if you have any problems while taking Alprim even if you do not think the problems are connected with the medicine or are not listed here. Other adverse effects reported involved the gastrointestinal and haematopoietic systems. Haleon, the company behind Panadol, recently launched PanaNatra, a line of non-paracetamol-based pain relief medication. These include: Your doctor can tell you what to do if you are taking any of these medicines. Do not take ALPRIM after the expiry date (EXP) printed on the pack. Owned and operated by AZoNetwork, 2000-2023. Alprim tablets contain the following inactive ingredients: lactose monohydrate, povidone, sodium starch glycollate, purified talc and magnesium stearate. AskMayoExpert. Phone: 1800 274 276, Knowing how to respond when someone says theyre struggling with their mental health or even suicidal can be daunting. The elderly and people with kidney problems may need smaller doses. Treatment of acute urinary tract infections caused by sensitive organisms. Tell your doctor or pharmacist that you are taking ALPRIM before you start taking any other medicine. Before starting any new medicine, tell your doctor or pharmacist that you are taking ALPRIM. There is no information concerning the right dose for children under the age of 6 years. Do not give ALPRIM to anyone else, even if they have the same condition as you. 6-24 months. Do not drive or operate machinery until you know how ALPRIM affects you. It works by stopping the ALPRIM belongs to a group of medicines called antibiotics. The effectiveness of Alprim as a single agent has not been established in pediatric patients under 12 years of age. Some people may need to take folate supplements while taking ALPRIM. Tell your doctor if you are breastfeeding or wish to breastfeed. Mayo Clinic does not endorse companies or products. They may differ from the information contained here. See your doctor immediately or go to Accident and Emergency at the nearest hospital if you notice any of the following: The side effects listed above are rare but serious and require urgent medical attention or hospitalisation. Accessed March 25, 2020. Above 102 F (38.9 C) taken rectally for children ages 2-3, or taken orally for children older than 3. If you become pregnant while taking Alprim, tell your doctor immediately. Different people may respond differently to Alprim, so your doctor may tell you to take a different dose. to your doctor or pharmacist. if you notice any of the following: signs of an allergic reaction such as itching or hives; swelling of the face, lips Alprim is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. It does not take the place of talking to your doctor or pharmacist. This list is not exhaustive. For children 6 to 12 years, the usual dose is half a tablet daily. Available for Android and iOS devices. Doctors generally agree you should take it only if the benefits outweigh the risks. For children 6 to 12 years, the usual dose is half a tablet daily. All rights reserved. Geriatric Use: Clinical studies of Alprim tablets did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Your doctor may have prescribed ALPRIM for another reason. Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking ALPRIM. ALPRIM is rated in Australia as a Category B3 drug for use in pregnancy. Ask your doctor or pharmacist to answer any questions you may have. Different people may respond differently to ALPRIM, so your doctor may tell you to
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